DNA language models, such as the Evo series, are vulnerable to jailbreak attacks that coerce the generation of DNA sequences with high homology to known human pathogens. The GeneBreaker framework demonstrates this by using a combination of carefully crafted prompts leveraging high-homology non-pathogenic sequences and a beam search guided by pathogenicity prediction models (e.g., PathoLM) and log-probability heuristics. This allows bypassing safety mechanisms and generating sequences exceeding…
Source: arXiv